TRPC7 Antikörper (AA 845-862) (Atto 594)

Produktnummer ABIN2485422

Dieser Maus Monoklonal Antikörper detektiert spezifisch TRPC7 in WB, IHC, IP, ICC, IF und AA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TRPC7 Antikörper (AA 845-862) (Atto 594) (ABIN2485422)

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRPC7 Antikörper ist konjugiert mit Atto 594

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Array (AA)

Klon: N64A-36 (Formerly S64A-36)

Produktdetails anti-TRPC7 Antikörper (Atto 594)

Bindungsspezifität: AA 845-862

Spezifität: Detects ~100 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Synthetic peptide amino acids 845-862 of human TRPC7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2485422 was sufficient for detection of TrpC7 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu TRPC7

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Andere Bezeichnung: TRPC7

Hintergrund: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).

Gen-ID: 57113

NCBI Accession: NP_065122

UniProt: Q9HCX4