GRIN1/NMDAR1 Antikörper (AA 42-361) (PerCP)

Produktnummer ABIN2483594

Produktdetails anti-GRIN1/NMDAR1 Antikörper (PerCP)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Bindungsspezifität: AA 42-361

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GRIN1/NMDAR1 Antikörper ist konjugiert mit PerCP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Detects ~105 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1

Klon: S308-48

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2483594 was sufficient for detection of NR1 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Andere Bezeichnung: GluN1 (GRIN1 Produkte)

Synonyme: GluN1 antikoerper, MRD8 antikoerper, NMDA1 antikoerper, NMDAR1 antikoerper, NR1 antikoerper, nmda1 antikoerper, nmdar1 antikoerper, GB19253 antikoerper, GRIN1 antikoerper, NMD-R1 antikoerper, Z16 antikoerper, GluRdelta1 antikoerper, GluRzeta1 antikoerper, M100174 antikoerper, Nmdar antikoerper, Rgsc174 antikoerper, NMDAR1.1 antikoerper, zgc:152678 antikoerper, glutamate ionotropic receptor NMDA type subunit 1 antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog antikoerper, NMDA receptor 1 antikoerper, G protein-regulated inducer of neurite outgrowth 1 antikoerper, glutamate receptor, ionotropic, NMDA1 (zeta 1) antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 1a antikoerper, GRIN1 antikoerper, grin1.S antikoerper, grin1 antikoerper, Grin1 antikoerper, Nmdar1 antikoerper, Gprin1 antikoerper, grin1a antikoerper

Hintergrund: The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short), two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits.

Gen-ID: 24408

NCBI Accession: NP_058706

UniProt: P35439

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity