Cullin 7 Antikörper (C-Term)

Produktnummer ABIN2470224

Produktdetails anti-Cullin 7 Antikörper

Target: Cullin 7 (CUL7)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Delipidation and Defibrination

Immunogen: Cullin 7 antibody was raised against a peptide near the C-Terminus of Cullin 7 (Human) Amino acids 1679-1698.

Anwendungsinformationen

Applikationshinweise: Cullin 7 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Serum, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store Cullin 7 antibody at 4 °C or -20 °C.

Details zu Cullin 7

Target: Cullin 7 (CUL7)

Andere Bezeichnung: Cullin 7 (CUL7 Produkte)

Synonyme: cullin-7 antikoerper, CUL7 antikoerper, Cullin-7 antikoerper, KIAA0076 antikoerper, dJ20C7.5 antikoerper, 2510004L20Rik antikoerper, AA409809 antikoerper, C230011P08Rik antikoerper, p185 antikoerper, p193 antikoerper, cullin 7 antikoerper, CUL7 antikoerper, Cul7 antikoerper

Hintergrund: Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 7 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 7 seems to be involved proteosomal degradation of proteins involved in endothelial proliferation and/or differentiation. Cullin 7 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1, FBXW8 and GLMN isoform 1. Cullin 7 interacts with a complex of SKP1 and FBXW8, but not with SKP1 alone.

Gen-ID: 9820

UniProt: Q14999

Pathways: ER-Nucleus Signaling