LMAN1 Antikörper (AA 270-470)

Produktnummer ABIN2468020

Produktdetails anti-LMAN1 Antikörper

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Bindungsspezifität: AA 270-470

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser LMAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Immunoaffinity Purified

Anwendungsinformationen

Applikationshinweise: ERGIC-53 protein antibody can be used for the detection of ERGIC-53 protein by Western Blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: LMAN1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Details zu LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Andere Bezeichnung: LMAN1 (LMAN1 Produkte)

Synonyme: ERGIC-53 antikoerper, ERGIC53 antikoerper, F5F8D antikoerper, FMFD1 antikoerper, MCFD1 antikoerper, MR60 antikoerper, gp58 antikoerper, 2610020P13Rik antikoerper, AI326273 antikoerper, AU043785 antikoerper, C730041J05 antikoerper, P58 antikoerper, p58 antikoerper, LMAN1 antikoerper, cpx-iii antikoerper, cpxiii antikoerper, lman1 antikoerper, wu:fc54c09 antikoerper, wu:fi36e01 antikoerper, Xp58 antikoerper, lman1-a antikoerper, lectin, mannose binding 1 antikoerper, lectin, mannose-binding, 1 antikoerper, complexin 3 antikoerper, lectin, mannose binding 1 S homeolog antikoerper, LMAN1 antikoerper, Lman1 antikoerper, cplx3 antikoerper, lman1 antikoerper, lman1.S antikoerper

Hintergrund: FUNCTION: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.

DISEASE: Defects in LMAN1 are a cause of factor V and factor VIII combined deficiency (F5F8D) [MIM:227300], also known as multiple coagulation factor deficiency I (MCFD1). F5F8D is an autosomal recessive bleeding disorder characterized by coordinate reduction of both clotting proteins. Affected patients present with a moderate bleeding tendency and have factor V and factor VIII levels in the range of 5-30 % of normal.

Molekulargewicht: 57.5 kDa (calculated)

Gen-ID: 3998

NCBI Accession: NP_005561

UniProt: P49257