Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Aufreinigung
Affinity Purified
Immunogen
A synthetic peptide corresponding to the N-terminus 11-pyro E start point.
Isotyp
IgG
Applikationshinweise
ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Target
Amyloid-beta 11
Hintergrund
Pyroglutamic acid truncated amyloid beta 11-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyrE modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-beta. Pyroglutamic acid truncated amyloid beta 11-40/42 s exact involvement in the pathophysiology of Alzheimer s disease has not been established