NAPA Antikörper

Produktnummer ABIN2463756

Produktdetails anti-NAPA Antikörper

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAPA Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by Protein A/G affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAPA.

Anwendungsinformationen

Applikationshinweise: NAPA antibody can be used for detection of NAPA by ELISA at 1:75000. NAPA antibody can be used for detection of NAPA by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NAPA antibody at -20 °C.

Details zu NAPA

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Andere Bezeichnung: NAPA (NAPA Produkte)

Synonyme: SNAPA antikoerper, wu:fa26c04 antikoerper, zgc:63906 antikoerper, napb antikoerper, 1500039N14Rik antikoerper, AW209189 antikoerper, RA81 antikoerper, SNARE antikoerper, a-SNAP antikoerper, hyh antikoerper, alpha-SNAP antikoerper, Alpha-SNAP antikoerper, NSF attachment protein alpha antikoerper, N-ethylmaleimide-sensitive factor attachment protein, alpha b antikoerper, NSF attachment protein alpha L homeolog antikoerper, N-ethylmaleimide-sensitive factor attachment protein, alpha antikoerper, N-ethylmaleimide sensitive fusion protein attachment protein alpha antikoerper, soluble NSF attachment protein antikoerper, NAPA antikoerper, napab antikoerper, napa.L antikoerper, napa antikoerper, EHI_000300 antikoerper, Napa antikoerper, LOC102577508 antikoerper

Hintergrund: The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37 % , 60 %, and 67 % identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.

Molekulargewicht: 33 kDa

Gen-ID: 8775

NCBI Accession: NP_003818

UniProt: P54920

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization