RGS10 Antikörper

Produktnummer ABIN2463707

Produktdetails anti-RGS10 Antikörper

Target: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS10.

Anwendungsinformationen

Applikationshinweise: RGS10 antibody can be used for detection of RGS10 by ELISA at 1:1562500. RGS10 antibody can be used for detection of RGS10 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RGS10 antibody at -20 °C.

Details zu RGS10

Target: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Andere Bezeichnung: RGS10 (RGS10 Produkte)

Synonyme: MGC82511 antikoerper, RGS10 antikoerper, 2310010N19Rik antikoerper, regulator of G-protein signaling 10 antikoerper, regulator of G-protein signaling 10 L homeolog antikoerper, regulator of G protein signaling 10 antikoerper, regulator of G-protein signalling 10 antikoerper, RGS10 antikoerper, rgs10.L antikoerper, rgs10 antikoerper, Rgs10 antikoerper

Hintergrund: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 21 kDa, 20 kDa

Gen-ID: 6001

NCBI Accession: NP_001005339

UniProt: Q96GN0

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling