PADI2 Antikörper

Produktnummer ABIN2463506

Produktdetails anti-PADI2 Antikörper

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PADI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PADI2.

Anwendungsinformationen

Applikationshinweise: PADI2 antibody can be used for detection of PADI2 by ELISA at 1:12500. PADI2 antibody can be used for detection of PADI2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PADI2 antibody at -20 °C.

Details zu PADI2

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Andere Bezeichnung: PADI2 (PADI2 Produkte)

Synonyme: PADI2 antikoerper, PAD-H19 antikoerper, PAD2 antikoerper, PDI2 antikoerper, Pdi antikoerper, Pdi2 antikoerper, mKIAA0994 antikoerper, peptidyl arginine deiminase 2 antikoerper, peptidyl arginine deiminase, type II antikoerper, protein-arginine deiminase type-2 antikoerper, peptidyl arginine deiminase, type II S homeolog antikoerper, PADI2 antikoerper, padi2 antikoerper, LOC100357368 antikoerper, padi2.S antikoerper, Padi2 antikoerper

Hintergrund: PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. PADI2 is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 75 kDa

Gen-ID: 11240

NCBI Accession: NP_031391

UniProt: Q9Y2J8