METAP2 Antikörper

Produktnummer ABIN2463504

Produktdetails anti-METAP2 Antikörper

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human METAP2.

Anwendungsinformationen

Applikationshinweise: METAP2 antibody can be used for detection of METAP2 by ELISA at 1:312500. METAP2 antibody can be used for detection of METAP2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store METAP2 antibody at -20 °C.

Details zu METAP2

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Andere Bezeichnung: METAP2 (METAP2 Produkte)

Synonyme: metap2 antikoerper, MGC53792 antikoerper, METAP2 antikoerper, GB13458 antikoerper, DDBDRAFT_0190923 antikoerper, DDBDRAFT_0304991 antikoerper, DDB_0190923 antikoerper, DDB_0304991 antikoerper, 4930584B20Rik antikoerper, A930035J23Rik antikoerper, AI047573 antikoerper, AL024412 antikoerper, AU014659 antikoerper, Amp2 antikoerper, Mnpep antikoerper, p67 antikoerper, p67eIF2 antikoerper, MAP2 antikoerper, MNPEP antikoerper, wu:fb98h06 antikoerper, zgc:66250 antikoerper, methionyl aminopeptidase 2 L homeolog antikoerper, methionyl aminopeptidase 2 antikoerper, methionine aminopeptidase 2 antikoerper, methionine aminopeptidase antikoerper, methionyl aminopeptidase 2 S homeolog antikoerper, methionyl aminopeptidase 2b antikoerper, metap2.L antikoerper, METAP2 antikoerper, metap2 antikoerper, LOC551771 antikoerper, CAALFM_C604080WA antikoerper, Metap2 antikoerper, metap2.S antikoerper, metap2b antikoerper

Hintergrund: METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 53 kDa

Gen-ID: 10988

NCBI Accession: NP_006829

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling