FDFT1 Antikörper

Produktnummer ABIN2463197

Produktdetails anti-FDFT1 Antikörper

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FDFT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FDFT1.

Anwendungsinformationen

Applikationshinweise: FDFT1 antibody can be used for detection of FDFT1 by ELISA at 1:12500. FDFT1 antibody can be used for detection of FDFT1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FDFT1 antibody at -20 °C.

Details zu FDFT1

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Andere Bezeichnung: FDFT1 (FDFT1 Produkte)

Synonyme: FDFT1 antikoerper, DKFZp459C1712 antikoerper, SQS antikoerper, SS antikoerper, DGPT antikoerper, ERG9 antikoerper, fdft1 antikoerper, farnesyl-diphosphate farnesyltransferase 1 antikoerper, squalene synthase antikoerper, farnesyl diphosphate farnesyl transferase 1 antikoerper, FDFT1 antikoerper, fdft1 antikoerper, LOC100560926 antikoerper, Fdft1 antikoerper

Hintergrund: FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 48 kDa

Gen-ID: 2222

NCBI Accession: NP_004453

UniProt: P37268

Pathways: Regulation of Lipid Metabolism by PPARalpha