CES1 Antikörper

Produktnummer ABIN2462491

Produktdetails anti-CES1 Antikörper

Target: CES1 (Carboxylesterase 1 (CES1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CES1.

Anwendungsinformationen

Applikationshinweise: CES1 antibody can be used for detection of CES1 by ELISA at 1:312500. CES1 antibody can be used for detection of CES1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CES1 antibody at -20 °C.

Details zu CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Andere Bezeichnung: CES1 (CES1 Produkte)

Synonyme: ACAT antikoerper, CE-1 antikoerper, CEH antikoerper, CES2 antikoerper, HMSE antikoerper, HMSE1 antikoerper, PCE-1 antikoerper, REH antikoerper, SES1 antikoerper, TGH antikoerper, hCE-1 antikoerper, CESDD1 antikoerper, CES1 antikoerper, CES-K1 antikoerper, APLE antikoerper, PMPMEase antikoerper, CES antikoerper, carboxylesterase 1 antikoerper, liver carboxylesterase 1 antikoerper, liver carboxylesterase antikoerper, carboxylesterase 1 (monocyte/macrophage serine esterase 1) antikoerper, CES1 antikoerper, CpipJ_CPIJ013026 antikoerper, CpipJ_CPIJ016339 antikoerper, LOC100009551 antikoerper, LOC454097 antikoerper, LOC699486 antikoerper, LOC100050915 antikoerper

Hintergrund: CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.

Molekulargewicht: 62 kDa, 63 kDa, 62 kDa, 8 kDa

Gen-ID: 1066

NCBI Accession: NP_001020365

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process