DCP2 Antikörper

Produktnummer ABIN2462345

Produktdetails anti-DCP2 Antikörper

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP2.

Anwendungsinformationen

Applikationshinweise: DCP2 antibody can be used for detection of DCP2 by ELISA at 1:62500. DCP2 antibody can be used for detection of DCP2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DCP2 antibody at -20 °C.

Details zu DCP2

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Andere Bezeichnung: DCP2 (DCP2 Produkte)

Synonyme: DDBDRAFT_0185453 antikoerper, DDBDRAFT_0252811 antikoerper, DDB_0185453 antikoerper, DDB_0252811 antikoerper, 2410015D23Rik antikoerper, 5730537H01Rik antikoerper, AL118268 antikoerper, NUDT20 antikoerper, RGD1562909 antikoerper, mRNA-decapping enzyme 2 antikoerper, hypothetical protein antikoerper, decapping mRNA 2 antikoerper, CpipJ_CPIJ019463 antikoerper, PTRG_05936 antikoerper, dcp2 antikoerper, MCYG_05106 antikoerper, MGYG_07617 antikoerper, PGTG_03310 antikoerper, Tsp_04018 antikoerper, DCP2 antikoerper, Dcp2 antikoerper

Hintergrund: DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly (A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).

Molekulargewicht: 48 kDa

Gen-ID: 167227

NCBI Accession: NP_689837

UniProt: Q8IU60