PUF60 Antikörper

Produktnummer ABIN2462252

Produktdetails anti-PUF60 Antikörper

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUF60 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PUF60.

Anwendungsinformationen

Applikationshinweise: PUF60 antibody can be used for detection of PUF60 by ELISA at 1:312500. PUF60 antibody can be used for detection of PUF60 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PUF60 antibody at -20 °C.

Details zu PUF60

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Andere Bezeichnung: PUF60 (PUF60 Produkte)

Synonyme: FIR antikoerper, RoBPI antikoerper, SIAHBP1 antikoerper, fc21a05 antikoerper, wu:fc21a05 antikoerper, wu:fi43a08 antikoerper, 2410104I19Rik antikoerper, 2810454F19Rik antikoerper, Siahbp1 antikoerper, fe37c05 antikoerper, repressor antikoerper, si:ch211-12p8.2 antikoerper, si:zc12p8.2 antikoerper, wu:fb33e11 antikoerper, wu:fe37c05 antikoerper, zgc:86806 antikoerper, poly(U) binding splicing factor 60 antikoerper, poly-U binding splicing factor a antikoerper, poly-U binding splicing factor 60 antikoerper, poly-U binding splicing factor b antikoerper, PUF60 antikoerper, puf60a antikoerper, Puf60 antikoerper, puf60b antikoerper

Hintergrund: PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Molekulargewicht: 58 kDa

Gen-ID: 22827

NCBI Accession: NP_055096