NR2F2 Antikörper

Produktnummer ABIN2461905

Produktdetails anti-NR2F2 Antikörper

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2F2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.

Anwendungsinformationen

Applikationshinweise: NR2F2 antibody can be used for detection of NR2F2 by ELISA at 1:312500. NR2F2 antibody can be used for detection of NR2F2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR2F2 antibody at -20 °C.

Details zu NR2F2

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Andere Bezeichnung: NR2F2 (NR2F2 Produkte)

Synonyme: nr2f2 antikoerper, MGC52954 antikoerper, ARP1 antikoerper, COUPTFB antikoerper, COUPTFII antikoerper, NF-E3 antikoerper, NR2F1 antikoerper, SVP40 antikoerper, TFCOUP2 antikoerper, 2700033K02Rik antikoerper, 9430015G03Rik antikoerper, ARP-1 antikoerper, Aporp1 antikoerper, COUP-TF2 antikoerper, COUP-TFII antikoerper, EAR3 antikoerper, Tcfcoup2 antikoerper, Tfcoup2 antikoerper, fc94g08 antikoerper, svp40 antikoerper, svp[40] antikoerper, wu:fc94g08 antikoerper, nuclear receptor subfamily 2 group F member 2 L homeolog antikoerper, Nr2f2 protein antikoerper, nuclear receptor subfamily 2 group F member 2 antikoerper, nuclear receptor subfamily 2, group F, member 2 antikoerper, nr2f2.L antikoerper, nr2f2 antikoerper, NR2F2 antikoerper, Nr2f2 antikoerper

Hintergrund: NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.

Molekulargewicht: 45 kDa

Gen-ID: 7026

NCBI Accession: NP_066285

UniProt: P24468

Pathways: Steroid Hormone Mediated Signaling Pathway