MAGEA9 Antikörper

Produktnummer ABIN2461754

Produktdetails anti-MAGEA9 Antikörper

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAGEA9.

Anwendungsinformationen

Applikationshinweise: MAGEA9 antibody can be used for detection of MAGEA9 by ELISA at 1:62500. MAGEA9 antibody can be used for detection of MAGEA9 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAGEA9 antibody at -20 °C.

Details zu MAGEA9

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Andere Bezeichnung: MAGEA9 (MAGEA9 Produkte)

Synonyme: CT1.9 antikoerper, MAGE9 antikoerper, MAGEA9B antikoerper, MAGEA9 antikoerper, MAGE family member A9 antikoerper, melanoma antigen family A, 9B antikoerper, melanoma-associated antigen 9 antikoerper, MAGEA9 antikoerper, MAGEA9B antikoerper, LOC525400 antikoerper

Hintergrund: MAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This pseudogene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is possible that, in rare cases, a combination of two SNPs in this gene may result in an open reading frame encoding a functional enzyme which metabolizes codeine to morphine. This locus is part of a cluster of cytochrome P450 genes on chromosome 22q13.1.

Molekulargewicht: 35 kDa

Gen-ID: 4108

NCBI Accession: NP_005356

UniProt: P43362