NR1D2 Antikörper

Produktnummer ABIN2461740

Produktdetails anti-NR1D2 Antikörper

Target: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1D2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1D2.

Anwendungsinformationen

Applikationshinweise: NR1D2 antibody can be used for detection of NR1D2 by ELISA at 1:312500. NR1D2 antibody can be used for detection of NR1D2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR1D2 antibody at -20 °C.

Details zu NR1D2

Target: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Andere Bezeichnung: NR1D2 (NR1D2 Produkte)

Synonyme: BD73 antikoerper, EAR-1R antikoerper, RVR antikoerper, HZF-2 antikoerper, Rev-erb antikoerper, REV-ERBB antikoerper, NR1D2 antikoerper, rvr antikoerper, bd73 antikoerper, hzf2 antikoerper, ear-1r antikoerper, hs.37288 antikoerper, NR1D2-A antikoerper, Reverbbeta-A antikoerper, reverbb1 antikoerper, reverbb antikoerper, reverbb2 antikoerper, zgc:92019 antikoerper, nuclear receptor subfamily 1 group D member 2 antikoerper, nuclear receptor subfamily 1, group D, member 2 antikoerper, nuclear receptor subfamily 1, group D, member 2a antikoerper, nuclear receptor subfamily 1, group D, member 2b antikoerper, NR1D2 antikoerper, Nr1d2 antikoerper, nr1d2 antikoerper, nr1d2a antikoerper, nr1d2b antikoerper

Hintergrund: NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.

Molekulargewicht: 65 kDa

Gen-ID: 9975

NCBI Accession: NP_005117

UniProt: Q14995

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway