Paired Box 3 Antikörper

Produktnummer ABIN2460551

Produktdetails anti-Paired Box 3 Antikörper

Target: Paired Box 3 (PAX3)

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Paired Box 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX3.

Anwendungsinformationen

Applikationshinweise: PAX3 antibody can be used for detection of PAX3 by ELISA at 1:1562500. PAX3 antibody can be used for detection of PAX3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX3 antibody at -20 °C.

Details zu Paired Box 3

Target: Paired Box 3 (PAX3)

Andere Bezeichnung: PAX3 (PAX3 Produkte)

Synonyme: PAX3 antikoerper, cdhs antikoerper, hup2 antikoerper, pax-3 antikoerper, ws1 antikoerper, xpax3 antikoerper, Pax3 antikoerper, pax3 antikoerper, pax3b antikoerper, xPax3-B antikoerper, CDHS antikoerper, HUP2 antikoerper, WS1 antikoerper, WS3 antikoerper, Pax-3 antikoerper, Sp antikoerper, splotch antikoerper, zgc:92547 antikoerper, paired box 3 antikoerper, paired box 3 L homeolog antikoerper, paired box 3a antikoerper, PAX3 antikoerper, pax3 antikoerper, pax3.L antikoerper, Pax3 antikoerper, pax3a antikoerper

Hintergrund: PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Molekulargewicht: 53 kDa, 53 kDa, 56 kDa

Gen-ID: 5077

NCBI Accession: NP_852122

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation