ESR2 Antikörper

Produktnummer ABIN2460264

Produktdetails anti-ESR2 Antikörper

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ESR2.

Anwendungsinformationen

Applikationshinweise: ESR2 antibody can be used for detection of ESR2 by ELISA at 1:312500. ESR2 antibody can be used for detection of ESR2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ESR2 antibody at -20 °C.

Details zu ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Andere Bezeichnung: ESR2 (ESR2 Produkte)

Synonyme: ER-BETA antikoerper, ESR-BETA antikoerper, ESRB antikoerper, ESTRB antikoerper, Erb antikoerper, NR3A2 antikoerper, ER[b]1 antikoerper, zfER-beta1 antikoerper, zfER[b]1 antikoerper, erb2 antikoerper, CERB antikoerper, ERB antikoerper, erb antikoerper, esrb antikoerper, estrb antikoerper, nr3a2 antikoerper, ERbeta antikoerper, er-beta antikoerper, esr-beta antikoerper, ESR2 antikoerper, ERBETA antikoerper, er antikoerper, ER-beta antikoerper, ER[b] antikoerper, Estrb antikoerper, ER[b]2 antikoerper, ER[b]a antikoerper, zfER[b]2 antikoerper, zfER-beta2 antikoerper, Erb2 antikoerper, esr2 antikoerper, erbeta antikoerper, Esr2 antikoerper, ERBeta2 antikoerper, estrogen receptor 2 antikoerper, estrogen receptor 2b antikoerper, estrogen receptor beta 2 antikoerper, estrogen receptor 2 (beta) antikoerper, estrogen receptor 2a antikoerper, estrogen receptor beta antikoerper, ESR2 antikoerper, esr2b antikoerper, erb2 antikoerper, esr2 antikoerper, Esr2 antikoerper, esr2a antikoerper, erbeta antikoerper

Hintergrund: ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Molekulargewicht: 48 kDa, 55 kDa, 55 kDa, 59 kDa

Gen-ID: 2100

UniProt: Q92731

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling