SNF8 Antikörper

Produktnummer ABIN2460244

Produktdetails anti-SNF8 Antikörper

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNF8.

Anwendungsinformationen

Applikationshinweise: SNF8 antibody can be used for detection of SNF8 by ELISA at 1:1562500. SNF8 antibody can be used for detection of SNF8 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SNF8 antibody at -20 °C.

Details zu SNF8

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Andere Bezeichnung: SNF8 (SNF8 Produkte)

Synonyme: d11moh34 antikoerper, vps22 antikoerper, Dot3 antikoerper, EAP30 antikoerper, VPS22 antikoerper, D11moh34 antikoerper, RGD1310144 antikoerper, D11Moh34 antikoerper, D11MOH34 antikoerper, zgc:101578 antikoerper, SNF8, ESCRT-II complex subunit antikoerper, eap30 subunit of ell complex, putative antikoerper, EAP30 subunit of ELL complex antikoerper, SNF8, ESCRT-II complex subunit S homeolog antikoerper, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) antikoerper, snf8 antikoerper, TA17290 antikoerper, TVAG_107410 antikoerper, Bm1_05145 antikoerper, SNF8 antikoerper, Snf8 antikoerper, snf8.S antikoerper

Hintergrund: ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).

Molekulargewicht: 29 kDa

Gen-ID: 11267

NCBI Accession: NP_009172

UniProt: Q96H20