TAF15 Antikörper

Produktnummer ABIN2460174

Produktdetails anti-TAF15 Antikörper

Target: TAF15 (TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAF15.

Anwendungsinformationen

Applikationshinweise: TAF15 antibody can be used for detection of TAF15 by ELISA at 1:312500. TAF15 antibody can be used for detection of TAF15 by western blot at 3.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TAF15 antibody at -20 °C.

Details zu TAF15

Target: TAF15 (TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))

Andere Bezeichnung: TAF15 (TAF15 Produkte)

Synonyme: 2610111C21Rik antikoerper, 68kDa antikoerper, TAFII68 antikoerper, Taf2n antikoerper, Npl3 antikoerper, RBP56 antikoerper, TAF2N antikoerper, TATA-box binding protein associated factor 15 antikoerper, Taf15 antikoerper, TAF15 antikoerper

Hintergrund: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF15 encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas.

Molekulargewicht: 62 kDa

Gen-ID: 8148

NCBI Accession: NP_631961

UniProt: Q92804