NFKBIL2 Antikörper

Produktnummer ABIN2460131

Produktdetails anti-NFKBIL2 Antikörper

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKBIL2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFKBIL2.

Anwendungsinformationen

Applikationshinweise: NFKBIL2 antibody can be used for detection of NFKBIL2 by ELISA at 1:62500. NFKBIL2 antibody can be used for detection of NFKBIL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFKBIL2 antibody at -20 °C.

Details zu NFKBIL2

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Andere Bezeichnung: NFKBIL2 (NFKBIL2 Produkte)

Synonyme: IKBR antikoerper, NFKBIL2 antikoerper, 2810439M11Rik antikoerper, Nfkbil2 antikoerper, im:7145273 antikoerper, nfkbil2 antikoerper, tonsl antikoerper, tonsoku like, DNA repair protein antikoerper, tonsoku-like, DNA repair protein antikoerper, TONSL antikoerper, Tonsl antikoerper, tonsl antikoerper

Hintergrund: NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Molekulargewicht: 133 kDa

Gen-ID: 4796

NCBI Accession: NP_038460

UniProt: Q96HA7

Pathways: Maintenance of Protein Location