Cyclin T1 Antikörper

Produktnummer ABIN2460095

Produktdetails anti-Cyclin T1 Antikörper

Target: Cyclin T1 (CCNT1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin T1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCNT1.

Anwendungsinformationen

Applikationshinweise: CCNT1 antibody can be used for detection of CCNT1 by ELISA at 1:1562500. CCNT1 antibody can be used for detection of CCNT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCNT1 antibody at -20 °C.

Details zu Cyclin T1

Target: Cyclin T1 (CCNT1)

Andere Bezeichnung: CCNT1 (CCNT1 Produkte)

Synonyme: CG6292 antikoerper, Dmcyclin T antikoerper, Dmel\\CG6292 antikoerper, ORE-14 antikoerper, P-TEFb antikoerper, anon-74EFc antikoerper, dT antikoerper, p124 antikoerper, Cyclin-T1 antikoerper, ccnt antikoerper, cyct1 antikoerper, CCNT antikoerper, CYCT1 antikoerper, HIVE1 antikoerper, 2810478G24Rik antikoerper, AI115585 antikoerper, CycT1 antikoerper, fi75b02 antikoerper, si:dkey-18f23.10 antikoerper, wu:fi75b02 antikoerper, Cyclin T antikoerper, cyclin T1 antikoerper, cyclin T1 L homeolog antikoerper, CycT antikoerper, CCNT1 antikoerper, ccnt1 antikoerper, Ccnt1 antikoerper, ccnt1.L antikoerper

Hintergrund: CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 81 kDa

Gen-ID: 904

NCBI Accession: NP_001231

UniProt: O60563