APRT Antikörper

Produktnummer ABIN2460045

Produktdetails anti-APRT Antikörper

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APRT.

Anwendungsinformationen

Applikationshinweise: APRT antibody can be used for detection of APRT by ELISA at 1:312500. APRT antibody can be used for detection of APRT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store APRT antibody at -20 °C.

Details zu APRT

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Andere Bezeichnung: APRT (APRT Produkte)

Synonyme: Tb07.43M14.200 antikoerper, Tb07.43M14.180 antikoerper, C85684 antikoerper, AMP antikoerper, APRTD antikoerper, adenine phosphoribosyltransferase antikoerper, adenine phosphoribosyl transferase antikoerper, CND05020 antikoerper, Tb927.7.1790 antikoerper, Tb927.7.1780 antikoerper, Arnit_0941 antikoerper, Saut_1231 antikoerper, Fbal_1180 antikoerper, PH_RS07970 antikoerper, PF_RS08760 antikoerper, PAB_RS02560 antikoerper, Aprt antikoerper, APRT antikoerper

Hintergrund: Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 20 kDa

Gen-ID: 353

NCBI Accession: NP_000476

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process