SPO11 Antikörper

Produktnummer ABIN2459829

Produktdetails anti-SPO11 Antikörper

Target: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPO11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPO11.

Anwendungsinformationen

Applikationshinweise: SPO11 antibody can be used for detection of SPO11 by ELISA at 1:1562500. SPO11 antibody can be used for detection of SPO11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPO11 antibody at -20 °C.

Details zu SPO11

Target: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Andere Bezeichnung: SPO11 (SPO11 Produkte)

Synonyme: CT35 antikoerper, SPATA43 antikoerper, TOPVIA antikoerper, zgc:77876 antikoerper, AI449549 antikoerper, Meiotic recombination protein spo-11 antikoerper, SPO11, initiator of meiotic double stranded breaks antikoerper, SPO11 meiotic protein covalently bound to DSB antikoerper, spo-11 antikoerper, SPO11 antikoerper, Spo11 antikoerper, spo11 antikoerper

Hintergrund: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. It belongs to the TOP6A protein family. Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.

Molekulargewicht: 44 kDa

Gen-ID: 23626

NCBI Accession: NP_036576

UniProt: Q9Y5K1