FBXO8 Antikörper

Produktnummer ABIN2459823

Produktdetails anti-FBXO8 Antikörper

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXO8.

Anwendungsinformationen

Applikationshinweise: FBXO8 antibody can be used for detection of FBXO8 by ELISA at 1:62500. FBXO8 antibody can be used for detection of FBXO8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBXO8 antibody at -20 °C.

Details zu FBXO8

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Andere Bezeichnung: FBXO8 (FBXO8 Produkte)

Synonyme: FBXO8 antikoerper, T24I21.22 antikoerper, T24I21_22 antikoerper, zgc:136842 antikoerper, FBS antikoerper, FBX8 antikoerper, Fbx8 antikoerper, F-box protein 8 antikoerper, F-box and associated interaction domains-containing protein antikoerper, F-box protein 8 L homeolog antikoerper, FBXO8 antikoerper, fbxo8 antikoerper, AT2G16810 antikoerper, fbxo8.L antikoerper, Fbxo8 antikoerper

Hintergrund: FBXO8 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO8 belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor (s) (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor (s) (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Molekulargewicht: 37 kDa

Gen-ID: 26269

NCBI Accession: NP_036312

UniProt: Q9NRD0