KPNA3 Antikörper

Produktnummer ABIN2459794

Produktdetails anti-KPNA3 Antikörper

Target: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KPNA3.

Anwendungsinformationen

Applikationshinweise: KPNA3 antibody can be used for detection of KPNA3 by ELISA at 1:12500. KPNA3 antibody can be used for detection of KPNA3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KPNA3 antibody at -20 °C.

Details zu KPNA3

Target: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Andere Bezeichnung: KPNA3 (KPNA3 Produkte)

Synonyme: IPOA4 antikoerper, si:dz79f24.2 antikoerper, importin antikoerper, SRP1 antikoerper, SRP1gamma antikoerper, SRP4 antikoerper, hSRP1 antikoerper, ipoa4 antikoerper, srp1 antikoerper, srp1gamma antikoerper, srp4 antikoerper, karyopherin (importin) alpha 3 antikoerper, karyopherin alpha 3 (importin alpha 4) antikoerper, karyopherin subunit alpha 3 antikoerper, karyopherin alpha 3 (importin alpha 4) L homeolog antikoerper, Kpna3 antikoerper, kpna3 antikoerper, KPNA3 antikoerper, kpna3.L antikoerper

Hintergrund: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 58 kDa

Gen-ID: 3839

NCBI Accession: NP_002258

UniProt: O00505

Pathways: Protein targeting to Nucleus