MPP7 Antikörper

Produktnummer ABIN2459648

Produktdetails anti-MPP7 Antikörper

Target: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MPP7.

Anwendungsinformationen

Applikationshinweise: MPP7 antibody can be used for detection of MPP7 by ELISA at 1:62500. MPP7 antibody can be used for detection of MPP7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MPP7 antibody at -20 °C.

Details zu MPP7

Target: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Andere Bezeichnung: MPP7 (MPP7 Produkte)

Synonyme: 1110068J02Rik antikoerper, 2810038M04Rik antikoerper, 5430426E14Rik antikoerper, AI415104 antikoerper, Gm955 antikoerper, dlg3 antikoerper, hmp antikoerper, membrane palmitoylated protein 7 antikoerper, membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) antikoerper, membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) antikoerper, MPP7 antikoerper, Mpp7 antikoerper, mpp7a antikoerper

Hintergrund: MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).

Molekulargewicht: 65 kDa

Gen-ID: 143098

NCBI Accession: NP_775767

UniProt: Q5T2T1

Pathways: Cell-Cell Junction Organization