Gephyrin Antikörper

Produktnummer ABIN2459504

Produktdetails anti-Gephyrin Antikörper

Target: Gephyrin (GPHN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gephyrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GPHN.

Anwendungsinformationen

Applikationshinweise: GPHN antibody can be used for detection of GPHN by ELISA at 1:1562500. GPHN antibody can be used for detection of GPHN by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GPHN antibody at -20 °C.

Details zu Gephyrin

Target: Gephyrin (GPHN)

Andere Bezeichnung: GPHN (GPHN Produkte)

Synonyme: 5730552E08Rik antikoerper, AI662856 antikoerper, BC027112 antikoerper, C230040D23 antikoerper, GPH antikoerper, GPHRYN antikoerper, geph antikoerper, Geph antikoerper, GPHN antikoerper, GEPH antikoerper, HKPX1 antikoerper, gpgb1 antikoerper, DKFZp459M0825 antikoerper, gephyrin antikoerper, gephyrin L homeolog antikoerper, gephyrin a antikoerper, Gphn antikoerper, GPHN antikoerper, gphn.L antikoerper, gphna antikoerper, PTRG_08978 antikoerper, VDBG_00775 antikoerper, Tsp_03043 antikoerper, gphn antikoerper

Hintergrund: GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Molekulargewicht: 80 kDa

Gen-ID: 10243

NCBI Accession: NP_001019389

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development