DCP1B Antikörper

Produktnummer ABIN2459448

Produktdetails anti-DCP1B Antikörper

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCP1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP1B.

Anwendungsinformationen

Applikationshinweise: DCP1B antibody can be used for detection of DCP1B by ELISA at 1:62500. DCP1B antibody can be used for detection of DCP1B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DCP1B antibody at -20 °C.

Details zu DCP1B

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Andere Bezeichnung: DCP1B (DCP1B Produkte)

Synonyme: DCP1 antikoerper, hDcp1b antikoerper, B930050E02Rik antikoerper, RGD1562214 antikoerper, dcp1 antikoerper, dcp1b antikoerper, mitc1l antikoerper, si:ch211-87p6none antikoerper, decapping mRNA 1B antikoerper, decapping mRNA 1B L homeolog antikoerper, DCP1B antikoerper, Dcp1b antikoerper, dcp1b.L antikoerper, dcp1b antikoerper

Hintergrund: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).

Molekulargewicht: 68 kDa

Gen-ID: 196513

NCBI Accession: NP_689853

UniProt: Q8IZD4