QPCT Antikörper

Produktnummer ABIN2459227

Produktdetails anti-QPCT Antikörper

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser QPCT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human QPCT.

Anwendungsinformationen

Applikationshinweise: QPCT antibody can be used for detection of QPCT by ELISA at 1:62500. QPCT antibody can be used for detection of QPCT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store QPCT antibody at -20 °C.

Details zu QPCT

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Andere Bezeichnung: QPCT (QPCT Produkte)

Synonyme: GCT antikoerper, QC antikoerper, sQC antikoerper, QPCT antikoerper, 5730422A13Rik antikoerper, Qpctl1 antikoerper, RGD1562284 antikoerper, qpct antikoerper, glutaminyl-peptide cyclotransferase antikoerper, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) antikoerper, glutaminyl-peptide cyclotransferase L homeolog antikoerper, QPCT antikoerper, Qpct antikoerper, M6_Spy0443 antikoerper, M5005_Spy_0416 antikoerper, M28_Spy0404 antikoerper, CJA_2408 antikoerper, CCNA_02733 antikoerper, Tsp_03182 antikoerper, qpct.L antikoerper

Hintergrund: QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86 % identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 38 kDa

Gen-ID: 25797

NCBI Accession: NP_036545

UniProt: Q16769