PAICS Antikörper

Produktnummer ABIN2458982

Produktdetails anti-PAICS Antikörper

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAICS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAICS.

Anwendungsinformationen

Applikationshinweise: PAICS antibody can be used for detection of PAICS by ELISA at 1:312500. PAICS antibody can be used for detection of PAICS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAICS antibody at -20 °C.

Details zu PAICS

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Andere Bezeichnung: PAICS (PAICS Produkte)

Synonyme: cb293 antikoerper, sb:cb293 antikoerper, wu:fa28a05 antikoerper, GB14262 antikoerper, DDBDRAFT_0218550 antikoerper, DDBDRAFT_0230088 antikoerper, DDB_0218550 antikoerper, DDB_0230088 antikoerper, AIRC antikoerper, AS antikoerper, ADE2 antikoerper, ADE2H1 antikoerper, PAIS antikoerper, Ade2h1 antikoerper, Airc antikoerper, ade2 antikoerper, airc antikoerper, paics antikoerper, pais antikoerper, 2610511I09Rik antikoerper, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase antikoerper, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antikoerper, multifunctional protein ADE2 antikoerper, phosphoribosylaminoimidazole carboxylase antikoerper, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog antikoerper, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase antikoerper, PAICS antikoerper, paics antikoerper, LOC551966 antikoerper, Tsp_02239a antikoerper, Tsp_02239 antikoerper, CNE02500 antikoerper, purC/E antikoerper, Paics antikoerper, paics.2.L antikoerper

Hintergrund: PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 47 kDa

Gen-ID: 10606

NCBI Accession: NP_001072992

UniProt: P22234

Pathways: Chromatin Binding