CNTNAP1 Antikörper

Produktnummer ABIN2458937

Produktdetails anti-CNTNAP1 Antikörper

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTNAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CNTNAP1.

Anwendungsinformationen

Applikationshinweise: CNTNAP1 antibody can be used for detection of CNTNAP1 by ELISA at 1:1562500. CNTNAP1 antibody can be used for detection of CNTNAP1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CNTNAP1 antibody at -20 °C.

Details zu CNTNAP1

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Andere Bezeichnung: CNTNAP1 (CNTNAP1 Produkte)

Synonyme: CNTNAP1 antikoerper, CASPR antikoerper, CNTNAP antikoerper, NRXN4 antikoerper, P190 antikoerper, Caspr antikoerper, AI841080 antikoerper, NCP1 antikoerper, Nrxn4 antikoerper, p190 antikoerper, shm antikoerper, contactin associated protein 1 antikoerper, contactin associated protein-like 1 antikoerper, CNTNAP1 antikoerper, cntnap1 antikoerper, Cntnap1 antikoerper

Hintergrund: CNTNAP1 was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Molekulargewicht: 156 kDa

Gen-ID: 8506

NCBI Accession: NP_003623

UniProt: P78357

Pathways: Cell-Cell Junction Organization