Transferrin Receptor 2 Antikörper

Produktnummer ABIN2458932

Produktdetails anti-Transferrin Receptor 2 Antikörper

Target: Transferrin Receptor 2 (TFR2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transferrin Receptor 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFR2.

Anwendungsinformationen

Applikationshinweise: TFR2 antibody can be used for detection of TFR2 by ELISA at 1:62500. TFR2 antibody can be used for detection of TFR2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TFR2 antibody at -20 °C.

Details zu Transferrin Receptor 2

Target: Transferrin Receptor 2 (TFR2)

Andere Bezeichnung: TFR2 (TFR2 Produkte)

Synonyme: TFR2 antikoerper, Trfr2 antikoerper, HFE3 antikoerper, TFRC2 antikoerper, zgc:123043 antikoerper, transferrin receptor 2 antikoerper, TFR2 antikoerper, Tfr2 antikoerper, tfr2 antikoerper

Hintergrund: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 89 kDa

Gen-ID: 7036

NCBI Accession: NP_003218

UniProt: Q9UP52

Pathways: Transition Metal Ion Homeostasis