CELF6 Antikörper

Produktnummer ABIN2458550

Produktdetails anti-CELF6 Antikörper

Target: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BRUNOL6.

Anwendungsinformationen

Applikationshinweise: BRUNOL6 antibody can be used for detection of BRUNOL6 by ELISA at 1:62500. BRUNOL6 antibody can be used for detection of BRUNOL6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BRUNOL6 antibody at -20 °C.

Details zu CELF6

Target: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Andere Bezeichnung: BRUNOL6 (CELF6 Produkte)

Synonyme: BRUNOL6 antikoerper, 6330569O16Rik antikoerper, Brunol6 antikoerper, CUGBP Elav-like family member 6 antikoerper, CUGBP, Elav-like family member 6 antikoerper, CELF6 antikoerper, Celf6 antikoerper

Hintergrund: BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.

Molekulargewicht: 50 kDa

Gen-ID: 60677

NCBI Accession: NP_443072

UniProt: Q96J87