RBM5 Antikörper
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- Target Alle RBM5 Antikörper anzeigen
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RBM5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBM5.
- Top Product
- Discover our top product RBM5 Primärantikörper
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- Applikationshinweise
- RBM5 antibody can be used for detection of RBM5 by ELISA at 1:312500. RBM5 antibody can be used for detection of RBM5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RBM5 antibody at -20 °C.
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- Target
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
- Andere Bezeichnung
- RBM5 (RBM5 Produkte)
- Synonyme
- wu:fc25a08 antikoerper, wu:fe06f12 antikoerper, g15 antikoerper, h37 antikoerper, luca15 antikoerper, rbm5 antikoerper, rmb5 antikoerper, RBM5 antikoerper, G15 antikoerper, LUCA15 antikoerper, RMB5 antikoerper, D030069N10Rik antikoerper, RNA binding motif protein 5 antikoerper, RNA binding motif protein 5 S homeolog antikoerper, RNA binding motif protein 5 L homeolog antikoerper, rbm5 antikoerper, rbm5.S antikoerper, RBM5 antikoerper, rbm5.L antikoerper, Rbm5 antikoerper
- Hintergrund
- RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
- Molekulargewicht
- 92 kDa
- Gen-ID
- 10181
- NCBI Accession
- NP_005769
- UniProt
- P52756
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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