RENT1/UPF1 Antikörper

Produktnummer ABIN2458238

Produktdetails anti-RENT1/UPF1 Antikörper

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RENT1/UPF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UPF1.

Anwendungsinformationen

Applikationshinweise: UPF1 antibody can be used for detection of UPF1 by ELISA at 1:312500. UPF1 antibody can be used for detection of UPF1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UPF1 antibody at -20 °C.

Details zu RENT1/UPF1

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Andere Bezeichnung: UPF1 (UPF1 Produkte)

Synonyme: HUPF1 antikoerper, NORF1 antikoerper, RENT1 antikoerper, pNORF1 antikoerper, smg-2 antikoerper, B430202H16Rik antikoerper, PNORF-1 antikoerper, Rent1 antikoerper, Upflp antikoerper, rent1 antikoerper, wu:fi40f07 antikoerper, wu:fj48a01 antikoerper, zgc:55472 antikoerper, Tb05.3C6.50 antikoerper, AO090012000584 antikoerper, hupf1 antikoerper, norf1 antikoerper, pnorf1 antikoerper, upf1 antikoerper, UPF1, RNA helicase and ATPase antikoerper, UPF1 regulator of nonsense transcripts homolog (yeast) antikoerper, upf1 regulator of nonsense transcripts homolog (yeast) antikoerper, regulator of nonsense transcripts 1 antikoerper, Regulator of nonsense transcripts 1 antikoerper, UPF1 regulator of nonsense transcripts homolog S homeolog antikoerper, UPF1 antikoerper, Upf1 antikoerper, upf1 antikoerper, Tc00.1047053511317.30 antikoerper, Tb927.5.2140 antikoerper, TVAG_453890 antikoerper, TVAG_237840 antikoerper, AOR_1_1018194 antikoerper, HPB8_739 antikoerper, smg-2 antikoerper, upf1.S antikoerper

Hintergrund: UPF1 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. UPF1 is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 123 kDa

Gen-ID: 5976

NCBI Accession: NP_002902

UniProt: Q92900

Pathways: SARS-CoV-2 Protein Interaktom