MTA2 Antikörper
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- Target Alle MTA2 Antikörper anzeigen
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MTA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTA2.
- Top Product
- Discover our top product MTA2 Primärantikörper
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- Applikationshinweise
- MTA2 antibody can be used for detection of MTA2 by ELISA at 1:312500. MTA2 antibody can be used for detection of MTA2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTA2 antibody at -20 °C.
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- Target
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
- Andere Bezeichnung
- MTA2 (MTA2 Produkte)
- Synonyme
- MTA1L1 antikoerper, PID antikoerper, fd61b05 antikoerper, wu:fd61b05 antikoerper, wu:fi29g02 antikoerper, zgc:63487 antikoerper, pid antikoerper, mta1l1 antikoerper, MTA2 antikoerper, DKFZp470E0911 antikoerper, AW550797 antikoerper, Mata1l1 antikoerper, Mta1l1 antikoerper, mmta2 antikoerper, metastasis associated 1 family member 2 antikoerper, metastasis associated 1 family, member 2 antikoerper, metastasis-associated gene family, member 2 antikoerper, metastasis associated 1 family member 2 L homeolog antikoerper, MTA2 antikoerper, mta2 antikoerper, Mta2 antikoerper, mta2.L antikoerper
- Hintergrund
- MTA2 may be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Molekulargewicht
- 75 kDa
- Gen-ID
- 9219
- NCBI Accession
- NP_004730
- UniProt
- O94776
- Pathways
- Chromatin Binding
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