Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) Antikörper

Details zu Produkt Nr. ABIN2457883, Anbieter: Anmelden zum Anzeigen
Antigen
  • ARRX
  • Arr4
  • Car
  • Carfl
  • Carr
  • arrestin 3
  • arrestin 3, retinal (X-arrestin) L homeolog
  • arrestin 3, retinal (X-arrestin)
  • arrestin 3, retinal
  • ARR3
  • arr3.L
  • arr3
  • Arr3
Epitop
C-Term
20
6
4
2
2
2
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
51
10
4
1
Wirt
Kaninchen
30
13
6
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
37
29
14
5
4
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen ARR3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ARR3.
Isotyp IgG
Spezifität ARR3 antibody is human, mouse and rat reactive. At least three isoforms of ARR3 are known to exist. This antibody is predicted to not cross-react with other members of the arrestin protein family.
Reinigung ARR3 antibody is affinity chromatography purified via peptide column.
Andere Bezeichnung ARR3 (ARR3 Antibody Abstract)
Hintergrund Arrestin 3 (ARR3) belongs to the Arrestin family of proteins that function as negative regulators of G protein-coupled receptor (GPCR) signaling (1,2). ARR3 binds the c-Jun N-terminal kinase 3 (JNK3) and scaffolds the apoptosis signal-regulating kinase 1 (ASK1)-MAPK kinase4-JNK3 cascade in a receptor-independent fashion, promoting JNK3 phosphorylation (3,4). ARR3 also mediates the internalization of the C-C chemokine receptor CCR7 upon the binding of its ligand CCL19, but not CCL21, suggesting that it helps mediate CCR7 receptor desensitization (5).
Molekulargewicht Predicted: 43 kDa

Observed: 47 kDa
Gen-ID 407
NCBI Accession NP_004303
UniProt P36575
Pathways Phototransduction, Thromboxane A2 Receptor Signaling
Applikations-hinweise ARR3 antibody can be used for detection of ARR3 by Western blot at 0.5 - 1 μg/mL.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer PBS containing 0.02 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Can be stored at 4 °C for three months and -20 °C, stable for up to one year.
Bilder des Herstellers
Western Blotting (WB) image for anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibody (ABIN2457883) anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibody
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