Avian Influenza Hemagglutinin 3 Antibody is affinity chromatography purified via peptide column.
Immunogen
Avian Influenza Hemagglutinin 3 antibody was raised against a synthetic peptide corresponding to 14 amino acids near the center of the Hemagglutinin protein Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
HA
Reaktivität: Influenza A Virus H1N1, Virus
ELISA, WB, IF (p), IF (cc), IHC (fro), IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Avian Influenza Hemagglutinin 3 antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Can be stored at 4 °C for three months and -20 °C, stable for up to one year.
hemagglutinin antikoerper, Hemagglutinin antikoerper, HA antikoerper, HA antikoerper, ha antikoerper
Substanzklasse
Influenza Protein
Hintergrund
Avian Influenza Hemagglutinin 3 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.