ASH2L Antikörper

Produktnummer ABIN2429543

Produktdetails anti-ASH2L Antikörper

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASH2L Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ASH2L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Andere Bezeichnung: ASH2L (ASH2L Produkte)

Synonyme: ASH2 antikoerper, ASH2L1 antikoerper, ASH2L2 antikoerper, Bre2 antikoerper, fb34c06 antikoerper, fe38b04 antikoerper, fi20h02 antikoerper, wu:fb34c06 antikoerper, wu:fe38b04 antikoerper, wu:fi20h02 antikoerper, zgc:171444 antikoerper, ASH2L antikoerper, ash2-like antikoerper, ASH2 like histone lysine methyltransferase complex subunit antikoerper, ash2 (absent, small, or homeotic)-like (Drosophila) antikoerper, ash2 (absent, small, or homeotic)-like L homeolog antikoerper, ASH2L antikoerper, Ash2l antikoerper, ash2l antikoerper, ash2l.L antikoerper

Hintergrund: The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60 % homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami.