STRADB Antikörper

Produktnummer ABIN2429143

Produktdetails anti-STRADB Antikörper

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human STRADB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Andere Bezeichnung: STRADB (STRADB Produkte)

Synonyme: Als2cr2 antikoerper, RGD1559449 antikoerper, als2cr2 antikoerper, MGC82468 antikoerper, STRADB antikoerper, ALS2CR2 antikoerper, AA792893 antikoerper, B830008M19 antikoerper, D1Ucla2 antikoerper, ILPIP antikoerper, ILPIPA antikoerper, PRO1038 antikoerper, Papk antikoerper, Syradb antikoerper, CALS-21 antikoerper, PAPK antikoerper, STE20-related kinase adaptor beta antikoerper, STE20-related kinase adaptor beta L homeolog antikoerper, Stradb antikoerper, STRADB antikoerper, stradb.L antikoerper

Hintergrund: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: Calculated MW: 47/31

Pathways: AMPK Signaling