Nebulin Antikörper

Produktnummer ABIN2426729

Produktdetails anti-Nebulin Antikörper

Target: Nebulin (NEB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nebulin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human NEB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Nebulin

Target: Nebulin (NEB)

Andere Bezeichnung: NEB (NEB Produkte)

Synonyme: im:6904860 antikoerper, im:7001777 antikoerper, im:7144538 antikoerper, im:7150492 antikoerper, wu:fc33b04 antikoerper, si:ch211-168m7.5 antikoerper, NEB antikoerper, NEB177D antikoerper, NEM2 antikoerper, AI595938 antikoerper, nebulin antikoerper, neb antikoerper, NEB antikoerper, Neb antikoerper, LOC100516703 antikoerper

Substanzklasse: Chemical

Hintergrund: This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4 % of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.

NCBI Accession: NP_001157979