CLDN8 Antikörper

Produktnummer ABIN2425955

Produktdetails anti-CLDN8 Antikörper

Target: CLDN8 (Claudin 8 (CLDN8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human CLDN8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CLDN8

Target: CLDN8 (Claudin 8 (CLDN8))

Andere Bezeichnung: Claudin 8 (CLDN8 Produkte)

Synonyme: zgc:91900 antikoerper, wu:fa01e05 antikoerper, CLDN8 antikoerper, AI648025 antikoerper, claudin 8 antikoerper, CLDN8 antikoerper, cldn8 antikoerper, Cldn8 antikoerper

Hintergrund: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.

NCBI Accession: NP_955360

Pathways: Hepatitis C