DDIT4 Antikörper
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- Target Alle DDIT4 Antikörper anzeigen
- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DDIT4 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human DDIT4
- Isotyp
- IgG
- Top Product
- Discover our top product DDIT4 Primärantikörper
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anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 20-49), (N-Term) antibody
DDIT4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB12592 unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 198-227), (C-Term) antibodyDDIT4 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB11618 unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-232) antibodyDDIT4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (N-Term) antibodyDDIT4 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-232) antibodyDDIT4 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (pThr23), (pThr25) antibodyDDIT4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 45-94) antibodyDDIT4 Reaktivität: Human, Ratte, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (C-Term), (N-Term) antibodyDDIT4 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.8 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Handhabung
- Avoid freeze / thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
- Andere Bezeichnung
- DDIT4 (DDIT4 Produkte)
- Synonyme
- redd1 antikoerper, Dig2 antikoerper, REDD-1 antikoerper, REDD1 antikoerper, 5830413E08Rik antikoerper, AA415483 antikoerper, Rtp801 antikoerper, dig2 antikoerper, rtp801 antikoerper, sb:cb821 antikoerper, zgc:64114 antikoerper, DNA damage inducible transcript 4 antikoerper, DNA-damage-inducible transcript 4 antikoerper, DNA damage inducible transcript 4 S homeolog antikoerper, ddit4 antikoerper, DDIT4 antikoerper, Ddit4 antikoerper, ddit4.S antikoerper
- Hintergrund
- REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
- Pathways
- Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process
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