Dynactin 4 Antikörper

Produktnummer ABIN2423287

Produktdetails anti-Dynactin 4 Antikörper

Target: Dynactin 4 (DCTN4)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynactin 4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human DCTN4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dynactin 4

Target: Dynactin 4 (DCTN4)

Andere Bezeichnung: DCTN4 (DCTN4 Produkte)

Synonyme: DYN4 antikoerper, P62 antikoerper, MGC84654 antikoerper, zgc:112431 antikoerper, MGC97564 antikoerper, 1110001K06Rik antikoerper, 4930547K17Rik antikoerper, C130039E17Rik antikoerper, p62 antikoerper, dynactin subunit 4 antikoerper, dynactin subunit 4 L homeolog antikoerper, dynactin 4 antikoerper, dynactin 4, putative antikoerper, DCTN4 antikoerper, Dctn4 antikoerper, dctn4.L antikoerper, dctn4 antikoerper, PKH_031720 antikoerper

Hintergrund: Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.