ARL6IP1 Antikörper

Produktnummer ABIN2422671

Produktdetails anti-ARL6IP1 Antikörper

Target: ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL6IP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ARL6IP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ARL6IP1

Target: ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))

Andere Bezeichnung: ARL6IP1 (ARL6IP1 Produkte)

Synonyme: arl6ip antikoerper, MGC56593 antikoerper, zgc:56593 antikoerper, zgc:77873 antikoerper, ARL6IP antikoerper, aip1 antikoerper, armer antikoerper, ARL6IP1 antikoerper, MGC85055 antikoerper, MGC139614 antikoerper, DKFZp459O112 antikoerper, AIP1 antikoerper, ARMER antikoerper, AIP-6 antikoerper, AL022945 antikoerper, AU042858 antikoerper, Aip-1 antikoerper, Arl6ip antikoerper, C85138 antikoerper, mKIAA0069 antikoerper, ADP-ribosylation factor-like 6 interacting protein 1 antikoerper, ADP ribosylation factor like GTPase 6 interacting protein 1 antikoerper, ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog antikoerper, ADP-ribosylation factor like GTPase 6 interacting protein 1 antikoerper, arl6ip1 antikoerper, ARL6IP1 antikoerper, arl6ip1.L antikoerper, Arl6ip1 antikoerper

Hintergrund: ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation.