Nephrin Antikörper (AA 451-550)

Produktnummer ABIN2177857

Produktdetails anti-Nephrin Antikörper

Target: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Bindungsspezifität: AA 451-550

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nephrin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität: Human

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nephrin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Nephrin Antikörper (ABIN2177857)

Wang, Feng, He, Sun, He, Jin: "miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury." in: Bioengineered, (2021) (PubMed).

Chen, Cheng, Chen, Shao, Sung, Chiang, Yang, Lin, Sun, Sheu, Chang, Lee, Yip: "Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats." in: Oncotarget, Vol. 8, Issue 59, pp. 100002-100020, (2018) (PubMed).

Details zu Nephrin

Target: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Andere Bezeichnung: Nephrin (NPHS1 Produkte)

Synonyme: NPHS1 antikoerper, nphs1l antikoerper, nphs1 antikoerper, CNF antikoerper, NPHN antikoerper, nephrin antikoerper, NephrinB antikoerper, NPHS1, nephrin antikoerper, nephrosis 1, congenital, Finnish type (nephrin) antikoerper, NPHS1 nephrin S homeolog antikoerper, nephrin antikoerper, NPHS1 nephrin antikoerper, nephrosis 1, nephrin antikoerper, NPHS1 antikoerper, nphs1 antikoerper, nphs1.S antikoerper, LOC5579127 antikoerper, Nphs1 antikoerper

Hintergrund:

Synonyms: CNF, NPHN, nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1

Background: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).

Gen-ID: 4868

UniProt: O60500

Pathways: Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development