HHV DNA Polymerase Catalytic Subunit (AA 1131-1235) Antikörper (Alexa Fluor 350)

Produktnummer ABIN2175765

Produktdetails

Target: HHV DNA Polymerase Catalytic Subunit

Bindungsspezifität: AA 1131-1235

Reaktivität: Human Herpesvirus 1 (HHV-1), Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit

Kreuzreaktivität: Virus

Kreuzreaktivität (Details): HHV1

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: HHV DNA Polymerase Catalytic Subunit

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: DPOL_HHV11, DNA polymerase catalytic subunit, UL30, HHV1gp046.

Background: Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.