TSH receptor Antikörper (AA 21-413) (HRP)

Produktnummer ABIN1994307

Produktdetails anti-TSH receptor Antikörper (HRP)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Bindungsspezifität: AA 21-413

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Thyrotropin receptor protein (21-413AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSHR (TSHR Produkte)

Synonyme: CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper

Hintergrund:

Background: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

Aliases: CHNG1 antibody, hTSHR I antibody, hTSHRI antibody, LGR 3 antibody, LGR3 antibody, MGC75129 antibody, Seven transmembrane helix receptor antibody, Thyroid adenoma hyperfunctioning antibody, Thyroid carcinoma with thyrotoxicosis antibody, Thyroid stimulating hormone receptor antibody, Thyroid stimulating hormone receptor, isoform 2 antibody, Thyroid-stimulating hormone receptor antibody, Thyrotropin receptor antibody, Thyrotropin receptor I antibody, Thyrotropin receptor I, hTSHR I antibody, TSH R antibody, TSH Receptor antibody, TSH-R antibody, TSHR antibody, TSHR_HUMAN antibody

UniProt: P16473

Pathways: Thyroid Hormone Synthesis