ZNF219 Antikörper (N-Term)

Produktnummer ABIN1888235

Produktdetails anti-ZNF219 Antikörper

Target: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF219 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: ZFP219 antibody was raised against an 18 amino acid peptide near the amino terminus of human ZFP219.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ZNF219

Target: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Andere Bezeichnung: ZFP219 (ZNF219 Produkte)

Synonyme: ZNF219 antikoerper, ZFP219 antikoerper, Znf219 antikoerper, 2010302A17Rik antikoerper, zinc finger protein 219 antikoerper, ZNF219 antikoerper, Zfp219 antikoerper

Hintergrund: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor.Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis.ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus.Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
Synonyms: Zinc finger protein 219, ZNF219

NCBI Accession: NP_001095142